Reglutide Injection | 1.34mg/ml | Type 2 Diabetes Mellitus | Semaglutide
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Reglutide 1.34mg/ml Injection

Generic: Semaglutide

Type: Injection

Pack Size: 1 Pc

Reglutide Injection/Semaglutide is used to treat adults (aged 18 years and older) with type 2 diabetes when diet and exercise are not enough to control blood sugar levels.


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Discount Price: ৳ 4650
MRP: ৳ 5000 7% Off

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✅ Description:

  • Glucagon-like Peptide-1 Receptor Agonist (GLP-1 RA): Mimics GLP-1 hormone, stimulating insulin production and reducing blood sugar.
  • Approved for over 15 years to treat Type 2 diabetes.
  • Acts on brain areas suppressing appetite and inducing a feeling of fullness.
  • When combined with diet and exercise, it leads to significant weight loss.
  • Studies show significant weight loss, with 15% body weight loss in half of the participants and 20% in nearly a third after 68 weeks.
  • Weight tends to be regained after stopping semaglutide
  • BMI of 27kg/m2 or greater: with one weight-related condition (e.g., high blood pressure, Type 2 diabetes, high cholesterol).
  • BMI of 30kg/m2 or greater.
  • Consult Primary Care Physician (PCP): Essential for personalized guidance based on medical history.
  • For Diabetic Individuals: Discuss acceptable and safe combinations with existing diabetes medications.

Safety Advices


Alcohol
UNSAFE

Avoid alcohol intake. Alcohol may worsen side effects, such as lactic acidosis, and increase the risk of developing low blood sugar levels.


Pregnancy
SAFE IF PRESCRIBED

Reglutide Injection is not recommended during pregnancy. The impact on the unborn baby is unknown. Discuss any concerns with your doctor.


Breastfeeding
SAFE

Avoid Reglutide Injection use during breastfeeding. It is unclear whether Reglutide Injection passes into breast milk. Discuss concerns with your doctor.


Driving
CAUTION

Exercise caution while driving. Blood sugar fluctuations, either too low or too high, may affect driving ability. Do not drive if these symptoms appear.


Kidney
CONSULT YOUR DOCTOR

Exercise caution in people with kidney impairment. Inform your doctor about kidney impairment/disorder history. Use will be prescribed if the benefits outweigh the risks.


Liver
CAUTION

Limited information for Reglutide Injection use in patients with liver impairment. Consult your doctor if you have concerns. The use will be prescribed if the benefits outweigh the risks.

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✔️ Uses:

Type 2 Diabetes Mellitus

✔️ Mode of Action:
  • GLP-1 Agonist: Enhances glucose-dependent insulin secretion, suppresses glucagon secretion, and slows gastric emptying.
✔️ Side Effects of Reglutide Injection
  • Common (>10%): Nausea, hypoglycemia.
  • 1-10%: Vomiting, diarrhea, abdominal pain, constipation, dyspepsia, flatulence, reflux.
  • <1%: Gastritis, cholelithiasis, fatigue, dysgeusia, dizziness, injection site reaction.
✔️ Quick Suggestions:
  • Eat at regular intervals.
  • Avoid taking a long gap between meals or snacks.
  • Monitor your blood sugar level regularly, especially during periods of significant fluctuations.
  • Invest in at least 150 minutes of moderate-intensity physical activity per week.
  • Include 15 minutes of exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (BMI) between 18.5 and 24.9.
  • Replace refined carbohydrate-containing foods with whole-grain options.
  • Increase the consumption of fruits, vegetables, and other fiber-enriched foods.
  • Reduce the intake of saturated fat from foods like chips, crisps, pastries, biscuits, and samosas.
  • Choose cooking oils containing omega-3 fatty acids for daily cooking.
  • Avoid stress as it may elevate blood sugar levels.
  • Adopt stress management techniques such as mindfulness, yoga, or meditation.
  • Opt for low-fat dairy products, such as low-fat yogurt, fat-free milk, and cheese.
  • Avoid drinking alcohol while on Semaglutide to reduce the risk of hypoglycemia and lactic acidosis.
  • Try to quit smoking.
  • Reduce the intake of carbohydrate-rich foods like potatoes, rice, mangoes, bread, and sugar.
  • Keep taking Semaglutide even if your blood sugar levels are controlled until your doctor advises otherwise.
  • Monitor your blood sugar frequently as recommended by your healthcare provider.
  • Regularly monitor pancreatic enzymes, such as lipase and amylase.
  • Avoid prolonged fasting when taking Semaglutide.
✔️ Indications:

Type 2 Diabetes Mellitus:

  • An adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Cardiovascular Risk Reduction:

  • To reduce the risk of major adverse cardiovascular events in adults with type 2 diabetes mellitus and established cardiovascular disease.

Chronic Weight Management:

  • An adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adult patients with:
    • BMI of 30 kg/m² or greater (Obesity) OR
    • BMI of 27 kg/m² or greater (Overweight) in the presence of at least one weight-related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia).
✔️ Pharmacology
  • GLP-1 analog with 94% sequence similarity to human GLP-1.
  • Acts as a GLP-1 receptor agonist.
  • Stimulates insulin secretion and lowers glucagon secretion in a glucose-dependent manner.
  • Inhibits inappropriate glucagon secretion.
  • Minor delay in gastric emptying.
  • Reduces body weight and fat mass by reducing appetite.
✔️ Dosage & Administration:

Subcutaneous Injection:

  • Starting dose: 0.25 mg once weekly for 4 weeks, then dose escalation over subsequent weeks.
  • Maintenance dose: 2.4 mg once weekly.

Administration:

  • SC Administration: Weekly injection in the abdomen, thigh, or upper arm.
  • Dosage: Start with 0.25 mg weekly for 4 weeks, then increase to 0.5 mg weekly. Can further increase to 1 mg weekly if needed.
  • Hepatic Impairment: No dosage adjustment is required.
  • Renal Impairment: No dosage adjustment is required.
✔️ Interaction
  • Hypoglycemia Risk: Coadministration with insulin secretagogues or insulin may increase the risk.
  • Oral Medications: Caution with concomitant oral medications due to delayed gastric emptying.
✔️ Do not use in patients with:
  • Personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
  • Hypersensitivity to Semaglutide.
✔️ Pregnancy & Lactation
  • Limited data; potential risks to the fetus. Use only if benefits justify risks.
  • Discontinue treatment at least 2 months before a planned pregnancy.
✔️ Precautions & Warnings
  • Thyroid C-Cell Tumors:
    • Unknown if Fitaro causes thyroid C-cell tumors; monitor for signs.
  • Pancreatitis:
    • Observe for signs; discontinue if suspected.
  • Diabetic Retinopathy Complications:
    • Monitor for progression in patients with a history of diabetic retinopathy.
  • Hypersensitivity:
    • Discontinue in case of hypersensitivity reactions.
  • Use in Special Populations:
    • Pediatric use not established.
    • Geriatric use: No overall differences in safety or efficacy.
    • No dose adjustment for renal or hepatic impairment.
✔️ Storage Conditions
  • Store in the refrigerator at 2°C to 8°C.
  • After the first use, store for 56 days in the refrigerator.
  • Do not freeze.
  • Unused cartridges may be used until the expiration date if kept in the refrigerator.
  • Keep away from heat and light; keep the pen cap on when not in use.
Frequently Asked Questions (FAQ)

Tell your doctor right away if you have a lump or swelling in your neck or throat, trouble swallowing or breathing, or if your voice gets hoarse.

History of medullary thyroid cancer. History of gallbladder disease. History of pancreatitis. Multiple endocrine neoplasia syndrome type 2 (MEN2)

Over-eating while taking semaglutide increases the risk of gastrointestinal side effects.

No

Sometimes it may indirectly affect the menstrual cycle. Potential effects of Semaglutide on periods include irregular cycles, amenorrhea, and hormonal imbalances.

No
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Check our pricing section for Reglutide 1.34mg/ml Injection price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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